The Motley Fool has a disclosure policy. 2/27/2023. They have two partners at Bristol Myers Squibb (BMY 0.83%) and Roche [Holding] (RHHBY 0.22%). They say they will not only cure arthritis, but also cancer in the future with their amazing technology. Bioscience & Technology Business CenterThe University of KansasLawrence, Kansas. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA. Boston-based Ikena said it expects to raise $125 million from the IPO. We are particularly excited by lorecivivint, which has the potential to be a first-in-class medicine that could confer both symptomatic and disease-modifying benefits to hundreds of millions of osteoarthritis sufferers worldwide.. Biosplice Therapeutics, Inc. Notable lists of unicorn companies are maintained by The Wall Street Journal, Fortune Magazine, CNNMoney/CB Insights, TechCrunch, PitchBook/Morningstar, and Tech in Asia. Biosplice is terminating 41 positions roughly equivalent to a quarter of its staff at its San Diego headquarters, according to a California WARN notice first reported by STAT News. Design said it expects to raise approximately $240 million from the IPO, a little bit higher than the $228 million the company previously anticipated. SAN DIEGO, Sept. 29, 2022 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on CLK/DYRK kinase modulation. That level of fanfare was nowhere to be found on Thursday, when the company added another $120 million to its coffers and quietly changed its name to Biosplice Therapeutics. Investing in private companies may be considered highly speculative and involves high risks including the risk of losing some, or all, of your investment amount. Unlock this article along with other benefits by subscribing to one of our paid plans. Nominate them for Endpoints annual report, Keytruda hits one primary endpoint for use before and after surgery in lung cancer. Our Private Market Specialists are available to answer any questions you might have and can help connect you with a buyer from our network of 125,000 accredited investors and institutions. Biosplice Therapeutics is in the medical research and development for tissue-level regeneration. The company asserts that medicines that can harness this process will help cure musculoskeletal, ummune and oncological disorders. Biosplice Therapeutics is in the medical research and development for tissue-level regeneration. Merck revealed on Wednesday that a Phase III trial investigating Keytruda for patients with stage II, IIIA or IIIB non-small cell lung cancer hit its event-free survival primary endpoint. Intra-articular (IA) injection into either knee with a therapeutic aim including, but not limited to, hyaluronic acid, platelet-rich plasma (PRP), and stem cell therapies within 26 weeks prior to Day 1 or IA glucocorticoids within 12 weeks prior to Day 1 SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for . About BiospliceBiosplice is developing first-in-class, small-molecule therapeutics based on pioneering science of alternative pre-mRNA splicing. 329 followers 290 connections. The Website is reserved exclusively for non-U.S. Please note the magic link is Investment opportunities posted on this website are "private placements" of securities that are not publicly traded, are subject to holding period requirements, and are intended for investors who do not need a liquid investment. Samumed made quite the entrance back in 2016, when it launched with some anti-aging programs and a whopping $12 billion valuation. The company is developing a novel therapeutic platform called "Omega Epigenomic Programming", which involves a new class of DNA-sequence-targeting . They have two partners at Bristol Myers Squibb ( BMY -1.71%) and Roche [Holding] ( RHHBY -2.31%). Biosplice Therapeutics is funded by 11 investors. See our Risk Factors for a more detailed explanation of the risks involved by investing through EquityZens platform. Alto is a full-service pharmacy powered by a team of experts dedicated to making your doctor's orders their own. Biosplice's drugs in clinical development include lorecivivint for osteoarthritis (in Phase 3), cirtuvivint for numerous cancers, and a broad pipeline that ranges from Alzheimer's disease to other degenerative conditions. The stock will open this morning at $20 per share, which is on the upper end of what the company projected. a short wikipedia entry. Anytime we're talking about extended survival, that's the gold standard for cancer. The Motley Fool owns shares of and recommends Bristol Myers Squibb. . X0002 is . About Mammoth Biosciences Stock. Learn More. Novartis can't make enough of it, A gene editing 3.0 player goes deep on cash, frontier science to put precision epigenetics to the big test, Decades after breakthrough, scientists still puzzling over mRNA delivery, Following the government's lead, Lilly caps out-of-pocket costs for insulin at $35 per month, Cell therapy biotech from Stanford CAR-T leader Crystal Mackall nabs $200M for PhII, Ex-AveXis crew trims staff at Chicago-area Jaguar Gene Therapy, Keytruda hits one primary endpoint for use before and after surgery in lung cancer, Amicus eyes Pompe approval; Atea ends Dengue work; 2seventy, Travere line up offerings. In December, Edgewise raised $95 million in a Series C financing round. April 15, 2021 10:55 ET The biotech boom in the early days of the pandemic helped fuel the rise of Taysha Gene Therapies and Jaguar Gene Therapy, but the winter freeze that followed has also caused a hunkering down for the biotechs, chaired by ex-AveXis CEO Sean Nolan. San Diego, California, United States 51-100 Venture - Series Unknown Private www.biosplice.com 5,337 Highlights Total Funding Amount $778M Contacts 69 Employee Profiles 7 Investors 11 Similar Companies 14 Find More Contacts for Biosplice Therapeutics That's in the same pathway as JAK, which we've talked about a lot. 10 stocks we like better than Bristol Myers SquibbWhen our award-winning analyst team has a stock tip, it can pay to listen. Now, the biotech is laying off a large swath of its staff as it undergoes a pipeline overhaul. Biosplice's drugs in clinical development include lorecivivint for osteoarthritis (in Phase 3), cirtuvivint for numerous cancers, and a broad pipeline that ranges from Alzheimer's disease to. Issi Rozen is as deeply embedded into the gene editing field as anyone in the buzzy Cambridge, MA biotech hub. We are particularly excited by lorecivivint, which has the potential to be a first-in-class medicine that could confer both symptomatic and disease-modifying benefits to hundreds of millions of osteoarthritis sufferers worldwide.. Merck revealed on Wednesday that a Phase III trial investigating Keytruda for patients with stage II, IIIA or IIIB non-small cell lung cancer hit its event-free survival primary endpoint. *Stock Advisor returns as of June 7, 2021. San Diego, California, United States. Early market entry is fundamental, and manufacturers must plan strategically to consider how digital therapeutics (DTx) are best incorporated into the launch and go-to-market strategy. Tom Jones take zinc after sex or personal release. Digital therapeutics support increased access to safe and effective therapies, providing an untapped opportunity for biopharmaceutical companies to maximize the value of medicinal assets and drive differentiation Alternative splicing is a process of creation of multiple mRNAs out of a single pre-mRNA. The company focuses on potential treatments for several diseases; its osteoarthritis program is its most advanced. Each of these companies announced their intentions this week. The data in the tables and charts is based on data from public sources and although we make every effort to compile the data, it may not coincide with the actual data of the issuer. Michael White, Ph.D. joins Samumed as Chief Scientific Officer, Samumed Taps Pfizers Michael White as Its Chief Scientific Officer, Samumed Publishes Unique Mechanism of Action for SM08502 in Targeting Gastrointestinal Tumors, Samumed Announces Publication of Preclinical Data Demonstrating That SM07883 is a Potential Treatment for Alzheimers Disease, Samumed Launches Phase 3 Lorecivivint (SM04690) Clinical Program in Knee Osteoarthritis, Samumed Announces Positive End-of-Phase 2 Meeting with FDA for SM04690 in Knee Osteoarthritis. Learn more at https://www.biosplice.com, Corporate Contact:Erich HorsleyBiosplice Therapeutics, Inc.erich.horsley@biosplice.com858-365-0200. Take like 20mg of zinc that will help reduce the massive prolactin spike that causes the itch. EDG-5506 is currently being assessed in a Phase I study. We are delighted to align with our new investors and board behind the immense therapeutic potential of Biosplice, said Cevdet Samikoglu, Chief Executive Officer of Biosplice. Ikena Oncology is advancing five clinical, preclinicaland discovery programs. Biosplice is developing first-in-class, small-molecule therapeutics based on pioneering science of alternative pre-mRNA splicing. Get stock recommendations, portfolio guidance, and more from The Motley Fool's premium services. After Novartis acquired AveXis, executives from the leading gene therapy biotech shuffled off to form new startups looking to repeat their Zolgensma story for other diseases. Biosplice Therapeutics, Inc. erich.horsley@biosplice.com 858-365-0200. Eli Lilly is looking to get ahead of any more federal action on insulin prices, announcing today that it will not only slash its most commonly used insulin by 70%, but cap out-of-pocket costs for those on commercial insurance at $35 per month just as the federal government recently did for those insured by Medicare. Total amount raised across all funding rounds, Total number of Crunchbase contacts associated with this organization, Total number of employee profiles an organization has on Crunchbase, Total number of investment firms and individual investors, Total number of organizations similar to the given organization, Descriptive keyword for an Organization (e.g. 308 followers 310 connections. Biosplice Therapeutics (formerly Samumed) "Biosplice's mission is to restore health by delivering first-in-class therapies that harness alternative splicing.". Biosplice Therapeutics. Biosplice Therapeutics, Inc. (formerly Samumed, LLC) is a private biopharmaceutical company based in San Diego, California.It was founded in 2008 by Osman Kibar.. Samumed's products in development target novel components of the Wnt signaling pathway. This investment round positions us to accelerate the development and launch of lorecivivint, our groundbreaking Phase 3 program in osteoarthritis. Internal digital and data science expertise is critical to developing a united value proposition that aligns the benefits of the digital and medicinal product. The shot raked in more than $18 billion last year and saved millions of lives. To make the world smarter, happier, and richer. Other biopharma companies will soon make their debut on stock exchanges. 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